Chapter 1748 - Genetic Optimization
Hello, Mr. Major General
Translator: Nyoi-Bo Studio Editor: Nyoi-Bo Studio
Lu Jin came to his laboratory table and took the DNA fragments of Qin Yaoguang and Wen Shouyi for verification and comparison.
Logically speaking, the accuracy of DNA identification when excluding the possibility of not being a parent-child relationship could be 100%.
In other words, when there was no blood relationship between two people, it was 100% accurate.
But to confirm that there was a direct parent-child relationship between the two, the accuracy was only 99.99999%.
The nine after this decimal point could vary according to the number of alleles intercepted.
However, under normal circumstances, when the accuracy of confirming that the two had a direct parent-child relationship was 99.99%, it could be confirmed that the two were direct parent-child relationships.
Lu Jinâs DNA test for Qin Yaoguang and Wen Shouyi was a full sequence.
This was not only a sequence that ordinary people could not afford, but even many people who were worth millions might not be able to afford it. Of course, it was not a big deal for Lu Jin.
He tested the full sequence, and the alleles that he cut off were as diverse as possible. Therefore, the accuracy of the paternity test that he tested was the highest, even if it was not 100%.
Before the test, he had to run electrophoresis. In simple terms, he had to make the DNA double helix âswimâ under a certain voltage. The speed of âswimmingâ of different functional DNA fragments was different, so he could separate different DNA fragments.
Then, he had to intercept the alleles and use software to analyze and compare them.
Lu Jin completed a whole set of procedures, and Gu Nianzhi watched with great interest from the side.
Even though she couldnât understand the pictures and data at all.
To be accurate, Lu Jin spent half an hour using software to analyze and compare the extracted allele fragments.
Finally, he let out a long sigh, â... They are biological mother and daughter.â
Gu Nianzhi was somewhat at a loss about this result.
She had been mentally prepared, but when this prediction was confirmed, she felt incredulous again.
â... Qin Yaoguang and Wen Shouyi?! Are they, biological mother and daughter?!â Gu Nianzhi was shocked. âThen they must have been surrogates? But why did she put Wen Shouyi in the Qin Orphanage? And then let Wen Dayou and his wife adopt her?!â
Lu Jin nodded, âSurrogates must be the only explanation. But why did Qin Yaoguang put Wen Shouyi in the orphanage? We could only ask Qin Yaoguang.â
â... But do you think she would tell the truth?â Gu Nianzhi asked quietly, her eyes were so dark that they couldnât see the bottom.
Lu Jin answered seriously, âI donât think she would. But I think this is her private matter. Do we have to ask?â
âYes,â Gu Nianzhi nodded seriously. âThis concerns the integrity of the courtâs evidence chain. Dad, you knew Qin Yaoguang better than I do. Can you reason why she would do this?â
Lu Jinâs eyes began to spin as soon as Gu Nianzhi started speaking in legal terms, just like how Gu Nianzhi had heard high-energy physics terms.
He said in a daze, âActually, I donât know much about Qin Yaoguang. But Iâve worked with her on experiments for so many years, so I roughly knew
about her attitude towards genetic research.â
âWhat attitude?â Gu Nianzhi questioned quickly.
âGenetic research was one of her specialties. She used her egg cells to synthesize fertilized eggs and had other women surrogate them to give birth. It was like catching a lab rat from a cage.â
âHave you ever seen an experimenter pour their love into a lab rat? Or treated them like a human?â
Gu Nianzhi pouted and mumbled, âI was a lab rat too, but if Qin Yaoguang used me for an experiment, she might as well throw me into an orphanage. Why didnât she use Wen Shouyi as an experiment?â
Lu Jinâs heart ached, and he didnât know how to comfort her.
In a moment of desperation, he subconsciously said, â... Maybe Wen Shouyi was the product of a failed experiment, so she wasnât used.â
Even though she wasnât comforted, it was still a miracle that her mood had improved...
Gu Nianzhi still had a straight face and said seriously, âLooks like I was useful.â
Lu Jin rubbed his hands awkwardly and pleaded, â... Nianzhi, Daddy knows that he was wrong...â
Gu Nianzhi was embarrassed and went forward to hold Lu Jinâs hand. She pulled him to the sofa and sat down, âDaddy, I was just joking. But...â
She rolled her eyes, âYou mean, Qin Yaoguang started researching embryo genes long before I was born?â
This question could be answered.
Lu Jin replied academically, âI donât have any concrete evidence, but since Wen Shouyi was born this way, Qin Yaoguang must have researched this.â
âAt that time, she didnât ask me for advice, so I didnât know that she had been doing this experiment for a long time.â
In other words, six years before Gu Nianzhi was born, Lu Jin still knew nothing about Qin Yaoguangâs secret experiment.
Gu Nianzhi nodded and continued to ask curiously, âBut why would she use her egg cells and Wen Dayouâs sperm to make a fertilized egg and give birth to an embryo? I thought she would use someone elseâs egg cells for research.â
Lu Jin smiled and responded casually, âIf she already had such an experiment, it wouldnât be her first time doing it, and it wouldnât be her last.â
âWhat do you mean?â Gu Nianzhiâs eyes suddenly lit up. âCould it be that she had done many research experiments in this area, and even used other peopleâs egg cells?â
âFrom a scientific point of view, thatâs for sure.â
Lu Jin patiently explained to her, âThis kind of human embryo experiment takes a long time. Generally, from fertilization to the birth of the fetus, it takes at least seven months, including premature babies.â
âNormally, it takes nine months. Together with the preparation before and after, the process of screening the pregnant men and women would take a year.â
âWhen an experiment takes a year from preparation to the result, the person experimenting would not only do one experiment at a time. Do you understand what I meant?â
Gu Nianzhi carefully digested Lu Jinâs words in her mind. After a while, she replied thoughtfully, âYou meant to say that doing such an experiment was no different from doing other biological experiments. We need to do a large number of experiments to screen out the effective results.â
âShe would prepare many of these fertilized eggs and transplant them into the pregnant womanâs stomach to get pregnant and then observe the results.â
Lu Jin nodded heavily, âExactly. The failure rate of experiments on biological genes was quite high. Therefore, she needed to accumulate the number of eggs to achieve a qualitative change from a quantitative change.â
âQin Yaoguang couldnât just use her egg cells for so many experiments,â Lu Jin used a scientific tone to explain the common sense of egg cells to Gu Nianzhi.
âAll mammalian females have immature egg cells in their ovaries when they were born.â
âThe number of female eggs was fixed at birth. It wonât increase, only gradually decrease.â
âSo it was impossible for Qin Yaoguang to conduct such a large-scale experiment using only her eggs. She must have used other peopleâs eggs before.â
Gu Nianzhi finally understood. She covered her mouth with her hand and gasped, âOh my god! How many embryo experiments did Qin Yaoguang conduct?! And how many Wen Shouyi and Gu Nianzhi were born this way?!â
Lu Jin smiled wryly, âNianzhi, did you think that such experiment would succeed easily?â
âDid you think itâs grafting?â
She thought so!
âWas it... Harder?â Gu Nianzhiâs long black eyelashes fluttered, and her big eyes were full of curiosity.
âNot just harder, it is very difficult,â Lu Jin didnât know how to explain it to Gu Nianzhi. âI just checked Wen Shouyiâs DNA sequence. I could see that Qin Yaoguang tried to genetically edit her, but it didnât work.â
Gu Nianzhi frowned, âThat means she started to genetically edit the embryo before she gave birth to me, or was it because of... He Zhichuâs illness?â
âI was not sure if she wanted Wen Shouyi to be born because of He Zhichuâs illness, but that could be the prototype of her idea. From then on, she started experimenting with this method.â
âBut you have to know that the human bodyâs genes are very complicated and huge. Decades ago, our understanding of genes was not as comprehensive as it is now, and the equipment and technology were not as advanced as they are now.â
âIn that kind of situation, there were very few fertilized eggs that could successfully get into the bed. It could be said that out of a thousand fertilized eggs that had been genetically edited, only one could successfully get into the bed and impregnate the mother.â
âAnd after these fertilized eggs developed into embryos, it would be amazing if one out of a hundred could be born successfully.â
Gu Nianzhi was very confused, âDid you mean, those embryos that were pregnant would miscarry?â
âOf course, and the probability of miscarriage would be very high,â Lu Jin sighed. âBecause these embryos were genetically edited, many of them had genetic defects.â
âThe human body has the function of self-selection. Embryos with genetic defects are called congenital defects. In a natural state, they would miscarry unless you use unconventional methods to preserve the fetus.â
âFor scientific experiments, we would not preserve the fetus of embryos with congenital defects. Did you understand what I mean? Very, very few children were successfully born and survived through genetic editing. I suspect that in Qin Yaoguangâs experiments, Wen Shouyi was probably the only embryo that was born and survived.â
Gu Nianzhi nodded slowly. She understood a little, but she had a new question.
â... You mentioned that embryos that had been genetically edited all had congenital genetic defects. So... am I the same as Wen Shouyi?â
Lu Jin shook his head first, then nodded and answered, âYouâre not. Wen Shouyi is.â
âWhy am I not?â Gu Nianzhi was very suspicious. âDad, donât say things like that just to comfort me.â
âI was not comforting you. You were questioning my professionalism!â Lu Jinâs eyes widened. âI edited your genes!â
âMy method was completely different from Qin Yaoguangâs. She was disrupting the sequence of the original gene fragments and only nurturing the genes with He Zhichuâs flaws.â
âOn the other hand, I was excluding those non-human viral genes based on your original genes, and then using your genes to expand and express them before adding them in.â
âAs a result of this, your genes had not been altered. Instead, it had been optimized to the greatest extent on the original basis.â
Lu Jin couldnât help feeling smug, âAs it turned out, I succeeded. You own the first perfect set of genes in human history! And itâs based on not changing your original genes!â
She was slowly getting confused in the conversation.
She knew every word Lu Jin said, but she couldnât understand it when they were put together.